Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 221037-98-5 | MDL No. : | MFCD01319015 |
Formula : | C6H6BIO2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | REEUXWXIMNEIIN-UHFFFAOYSA-N |
M.W : | 247.83 | Pubchem ID : | 2734362 |
Synonyms : |
|
Num. heavy atoms : | 10 |
Num. arom. heavy atoms : | 6 |
Fraction Csp3 : | 0.0 |
Num. rotatable bonds : | 1 |
Num. H-bond acceptors : | 2.0 |
Num. H-bond donors : | 2.0 |
Molar Refractivity : | 48.98 |
TPSA : | 40.46 Ų |
GI absorption : | High |
BBB permeant : | No |
P-gp substrate : | No |
CYP1A2 inhibitor : | No |
CYP2C19 inhibitor : | No |
CYP2C9 inhibitor : | No |
CYP2D6 inhibitor : | No |
CYP3A4 inhibitor : | No |
Log Kp (skin permeation) : | -6.76 cm/s |
Log Po/w (iLOGP) : | 0.0 |
Log Po/w (XLOGP3) : | 1.48 |
Log Po/w (WLOGP) : | -0.03 |
Log Po/w (MLOGP) : | 1.21 |
Log Po/w (SILICOS-IT) : | 0.24 |
Consensus Log Po/w : | 0.58 |
Lipinski : | 0.0 |
Ghose : | None |
Veber : | 0.0 |
Egan : | 0.0 |
Muegge : | 0.0 |
Bioavailability Score : | 0.55 |
Log S (ESOL) : | -2.69 |
Solubility : | 0.51 mg/ml ; 0.00206 mol/l |
Class : | Soluble |
Log S (Ali) : | -1.94 |
Solubility : | 2.87 mg/ml ; 0.0116 mol/l |
Class : | Very soluble |
Log S (SILICOS-IT) : | -2.24 |
Solubility : | 1.41 mg/ml ; 0.0057 mol/l |
Class : | Soluble |
PAINS : | 0.0 alert |
Brenk : | 2.0 alert |
Leadlikeness : | 1.0 |
Synthetic accessibility : | 2.68 |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P280-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302+H312+H332-H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In toluene;Reflux; | Into iodobenzeneboronic acid (186 g, 0.75 mol) and 700 (2 mL) were added to 1 L of a three-necked flask equipped with a reflux water separatorMl of toluene, heated to reflux water, when the system separated about 17.5-14.0 grams of water, and the system no longer continue to separate water,Stop the reaction. After cooling, the heptane is distilled to a non-flowing liquid to give crude tri-iodobenzene triol, which contains about 5-8percentbenzene. Can be directly into the next step reaction.Synthesis of aldehyde aldehyde phenylboronic acid:Under nitrogen protection, the above-obtained iodobenzeneboronic acid trimer was added to 500 ml of anhydrous tetrahydrofuranAfter the addition, the mixture was transferred to a 2 L three-necked flask and dimethylformamide (65.7 g, 0.90 mol) was added. Then cool the system to -75 ° C to -80 ° C, 609 ml (0.98 mol) of 1.6 M n-butyllithium hexane solution was slowly added dropwise, |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With pyridine; copper diacetate; In dichloromethane;Molecular sieve; under an oxygen balloon; | To a solution of 3-iodo-phenylboronic acid (991 mg, 4 mmol) and 1-benzofuran-6-ol (269 mg, 2 mmol) in dichloromethane (8 mL) was added copper acetate (363 mg, 2 mmol), pyridine (0.8 mL, 10 mmol) and 4A molecular sieves (300 mg). The reaction mixture was degassed and stirred under an oxygen balloon overnight. It was then filtered and concentrated. The crude product was purified on a silica gel column, eluting with ethyl acetate (0-10percent) in hexanes, to yield the desired product. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In tetrahydrofuran; for 0.25h;Heating / reflux; Molecular sieves; | A mixture of <strong>[221037-98-5]3-iodophenylboronic acid</strong> (15 g) and 1, 3-diphenyl-1, 3-propanediol (15 g) in tetrahydrofuran (150 ML) was heated to reflux for 15 min in the presence of molecular sieves. The mixture was filtered and the filtrate was concentrated under reduced pressure. The residue was crystallised from heptane-ethyl acetate (5: 1) to give the title compound (25.3 g) LCMS RT = 3.03 min. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With pyridine; copper diacetate; In dichloromethane; at 20℃;4A molecular sieves; | To a stirred solution of Intemediate 1 (1.9 g, 8.5 mmol) in dichloromethane (20 mL) was added 3- iodophenylboronic acid (3.0 g, 12.1 mmol), copper(II) acetate (2.0 g, 11 mmol), pyridine (3.2 mL, 40 mmol), and 4A molecular sieves (~2.5 g). The resulting mixture was stirred under an oxygen balloon at room temperature overnight. The reaction mixuture was filtered, washed with dichloromethane, and concentrated. The greenish crude product was purified on a silica gel column, eluting with ethyl acetate (20-50percent) in hexanes to afford the desired product. LCMS for C 19Hl 9103: calc. 422, observed 423 [M+H]. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
51% | Example 1.52; Preparation of the intermediate (4-bromo-2-methyl-2H-pyrazoI-3-yI)-(3-iodo-phenyl)- amine.A 500-mL round bottom flask was charged with toluene (50 mL), copper(IT) acetate (0.62 g, 3.41 mmol), myristic acid (1.17 g, 5.11 mmol), and roe-iodophenylboronic acid (5.00 g, 20.18 mmol) then stirred at room temperature for five minutes. While mixing, 2,6-lutidine (1.99 mL, 17.04 mmol) was added and allowed to stir for an additional 10 minutes. 3-amino-4-bromo- 2-methyl pyrazole (3.00 g, 17.04 mmol) was added then reaction mixture stirred at room temperature overnight. Ethyl acetate was added, washed with ammonium hydroxide, water and brine. The ammonium salt formed, suspended in the organic layer, was removed by filtration. The filtrate was washed with water twice, dried over MgSO4 and filtered. The solvent was removed under reduced pressure to yield a crude yellow oil, that was purified by column EPO <DP n="87"/>chromatography on silica gel (Biotage, hexanes/ethyl acetate, gradient elution) to afford (4- bromo-2-methyl-2H-pyrazol-3-yl)-(3-iodo-phenyl)-amine as a yellow solid. Yield: 3.25 g (51 percent). LCMS m/z (percent) = 378 (M+Eta 79Br, 100), 380 (M+Eta 81Br, 88). 1H NMR (400MHz, DMSO- d6): delta 8.15 (s, IH), 7.61 (s, IH), 7.09 (d, J=8.0 Hz, IH), 6.96 (dd, J=8.0, 8.0 Hz, IH), 6.90 (dd, J=I.8, 1.8 Hz, IH), 6.52 (dd, J=8.0, 1.6 Hz, IH), 3.63 (s, 3H). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98% | General procedure: NaN3 (1.2 equiv), CuSO4 (0.1 equiv), and boronic acids (1.2 equiv) in methanol (10 mL) were allowed to react for 1?4 h, followed by addition of water (10 mL), sodium ascorbate (0.5 equiv), and propargylated alpha-desmotroposantonin (1.0 equiv) [34]. The contents were stirred vigorously at room temperature for 2?8 h (as monitored by TLC analysis). After completion of the reaction, the contents diluted with water and extracted with ethyl acetate (3 times). The combined ethyl acetate extract was washed with brine, dried over anhydrous Na2SO4 and evaporated under reduced pressure on a rota vapour. The crude product obtained thus subjected was put to column chromatography (silica gel) with EtOAc:Hexane (15:85) mixture as eluent to afford the desired pure products in >97percent yields. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
81% | With [bis(acetoxy)iodo]benzene; triethylamine; 1,1'-carbonyldiimidazole; In dichloromethane; at 20℃; for 3h; | General procedure: To a mixture of benzoic acid (1 mmol), carbonyldiimidazole (1mmol), triethylamine, (5 mmol) and boronic acid (1 mmol) in dichlorormethane (5mL) were charged to PhI(OAc)2 (0.38g, 1.2 mmol). The reaction mixture was stirred at room temperature for 3h. After complete conversion, as indicated by TLC (9:1 Hexane:EtOAc), the reaction mixture was evaporated under reduced pressure and theresidue was purified by flash column chromatography on silica gel (2percent ethylacetate inpetroleum ether) to give the product. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
61.1% | With pyridine; pyridine N-oxide; oxygen; copper diacetate; In dichloromethane; at 20℃; for 72h;Molecular sieve; | Compound 3f was obtained from 2 using the proceduredescribed above for 3e, using 3-iodophenyl boronic acid. The crudeproduct was purified by chromatography on silica gel with CHCl3/hexane/acetone = 1:18:1 to provide 3f (522.7 mg, 61.1percent) as a beigepowder: mp: 175?176 C; 1H NMR (600 MHz, DMSO-d6) d ppm:8.22 (dd, J = 2.4, 8.6 Hz, 1H), 7.99 (dd, J = 2.9, 5.5 Hz, 2H), 7.93(dd, J = 2.9, 5.5 Hz, 2H), 7.89 (d, J = 8.8 Hz, 1H), 7.84 (d, J = 2.2 Hz,1H), 7.52 (d, J = 7.8 Hz, 1H), 7.40 (t, J = 2.0 Hz, 1H), 7.16 (t,J = 8.1 Hz, 1H), 7.10 (dd, J = 2.4, 8.2 Hz, 1H); FTIR(KBr) cm1:3480, 1734, 1715; EI-MS m/z: 486 [M]+; HR-MS: calcd forC20H11IN2O5 [M]+: 485.9713; found 485.9718. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
86% | With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water; at 80℃; for 8h;Inert atmosphere; | After 20 g (55.2 mmol) of Compound 1-4 was dissolved in 180 mL of tetrahydrofuran (THF) in a nitrogen atmosphere, 13.7 g (55.2 mmol) of <strong>[221037-98-5]3-iodophenylboronic acid</strong> and 13.7 g (Triphenylphosphine) palladium (0.64 g, 0.55 mmol) were added and stirred. 19.1 g (138 mmol) of saturated potassium carbonate in water was added, and the mixture was refluxed by heating at 80 DEG C for 8 hours. After the completion of the reaction, water was added to the reaction mixture, and the mixture was extracted with dichloromethane (DCM). The extract was dried over anhydrous MgSO 4, filtered and concentrated under reduced pressure. The thus-obtained residue was separated and purified by flash column chromatography to obtain 16.5 g (68percent) of a compound I-17. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
82% | With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In ethanol; water; toluene; at 110℃;Inert atmosphere; | 27.7 g of the brominated product of Reaction 44 and 19.0 g of iodobenzene boronic acid were added to2L three-necked flask, addDissolve 600mL of toluene and 150mL of ethanol.Pass nitrogen for 15 minutes and then add 104 mLAqueous solution of K2CO3 (3.0eq., 2M), most Afterwards 1.6 g of Pd(PPh3)4 (2 mol percent) was added.The temperature was raised to 110°C and the reaction ended overnight.Add activated carbon adsorption, suction filtration,Remove solvent, dry, recrystallize with toluene and ethanol,29.7 g of intermediate X are obtained (yield 82percent). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
76% | With copper(l) iodide; caesium carbonate; ethylenediamine; In toluene; for 24h;Reflux; | Compound D3 (5.97 g, 30.0 mmol), <strong>[221037-98-5]3-iodobenzeneboronic acid</strong> (8.67 g, 35 mmol), cuprous iodide (2.85 g, 15.0 mmol), ethylenediamine (0.90 mg, 15.0 mmol) were sequentially added to the reaction flask. , cesium carbonate (30.0g, 92.0mmol) and toluene(200 mL), stirred under reflux for 24 hours. After the reaction was completed, the reaction mixture was extracted with ethyl acetate.Concentrated under reduced pressure,The obtained crude product was subjected to column purification to yield Compound E3 (7.28 g, 76percent). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In diethyl ether; at 20℃;Inert atmosphere; Molecular sieve; | General procedure: To a Et2O solution of anorganoboronic acid (1.00 equiv) and 2,2-dimethylpropane-1,3-diol (neopentyl glycol)(1.02 equiv), 4A molecular sieves was added and the reaction mixture was stirred atroom temperature. After the reaction finished, the reaction mixture was filtered andconcentrated in vacuo. The residue was subjected to flash column chromatography(eluent: petroleum ether/ethyl acetate) or recrystallization to obtain the desired product |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
81% | With 1,2,2,3,4,4-hexamethylphosphetane 1-oxide; phenylsilane at 120℃; for 24h; Schlenk technique; Inert atmosphere; chemoselective reaction; |
Tags: 221037-98-5 synthesis path| 221037-98-5 SDS| 221037-98-5 COA| 221037-98-5 purity| 221037-98-5 application| 221037-98-5 NMR| 221037-98-5 COA| 221037-98-5 structure
[ 374790-98-4 ]
2-Fluoro-4-iodophenylboronic acid
Similarity: 0.72
[ 374790-98-4 ]
2-Fluoro-4-iodophenylboronic acid
Similarity: 0.72
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :