Home Chemistry Organic Building Blocks Fluorinated Building Blocks (2-Fluorophenyl)Methanol
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH2OH).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Hydrogenolysis: Phenylmethanol can be cleaved using hydrogen gas and a catalyst to form benzene and methanol.
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2-Fluoro-3-(trifluoromethyl)benzyl alcohol
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4-Fluoro-3-(hydroxymethyl)benzeneboronic acid
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(2-Fluoro-5-(trifluoromethyl)phenyl)methanol
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3,5-Difluoro-4-(hydroxymethyl)benzonitrile
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3-Fluoro-4-(hydroxymethyl)benzonitrile
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