Home Chemistry Organic Building Blocks Bromides 1,3-Dibromo-2,4-Difluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—F).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
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