Home Chemistry Heterocyclic Building Blocks Indazoles 1-(1H-Indazol-1-Yl)Ethan-1-One
Nucleophilic Substitution: The carbonyl carbon can undergo nucleophilic substitution reactions with various nucleophiles, such as amines or hydrazines, leading to the formation of substituted ketones or imines.
Reduction: The carbonyl group can be reduced to the corresponding alcohol using reducing agents such as sodium borohydride or lithium aluminum hydride.
Oxidation: The alcohol group can be oxidized to the corresponding carboxylic acid under appropriate conditions.
Acylation: The nitrogen atom in the indazole ring can undergo acylation reactions to form N-acyl derivatives.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Ring Closure: The ketone functionality can participate in ring-closure reactions under certain conditions, leading to the formation of cyclic compounds.
Amidation: The carbonyl group can react with amines to form amides under appropriate conditions.
Substitution Reactions: The indazole ring can undergo substitution reactions at the C2 or C3 position depending on the electrophile and reaction conditions.
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1-(5-Bromo-6-fluoro-1H-indazol-1-yl)ethanone
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Methyl 1-acetyl-3-methyl-1H-indazole-6-carboxylate
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Methyl 1-acetyl-1H-indazole-5-carboxylate
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