Home Chemistry Organic Building Blocks Benzyl Chlorides 1-(Chloromethyl)-2-Fluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —CH2Cl,—F).
Friedel-Crafts Alkylation: Chloromethylbenzene can undergo Friedel-Crafts alkylation reactions with suitable alkylating agents, leading to the introduction of alkyl groups onto the benzene ring.
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
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1-(Chloromethyl)-2,3,4,5,6-pentafluorobenzene
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1-(Chloromethyl)-2-fluoro-3-nitrobenzene
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