Home Chemistry Organic Building Blocks Chlorides 1-Chloro-3-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—NO2).
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Sulfonation: Nitrobenzene can be sulfonated to introduce a sulfonic acid group (-SO3H) onto the benzene ring. Sulfonation is carried out using concentrated sulfuric acid, which leads to the substitution of one of the hydrogen atoms on the ring.
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2-Chloro-4-nitro-1-(trifluoromethyl)benzene
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