Home Chemistry Heterocyclic Building Blocks Pyridines 2-Fluoro-3-Iodopyridine
Substitution Reactions: The fluorine and iodine atoms can undergo substitution reactions with various nucleophiles or electrophiles, leading to the formation of different functionalized pyridine derivatives.
Metal-Mediated Reactions: 2-fluoro-3-iodopyridine can undergo reactions with various transition metal catalysts, such as palladium or copper catalysts, to form cross-coupling products via Suzuki, Heck, or Sonogashira reactions.
Nucleophilic Aromatic Substitution (SNAr): The compound can undergo nucleophilic aromatic substitution reactions with strong nucleophiles, leading to the displacement of the fluorine or iodine atom.
Electrophilic Aromatic Substitution (SEAr): 2-fluoro-3-iodopyridine can react with electrophilic reagents, such as acylating or alkylating agents, leading to substitution of the hydrogen atom on the pyridine ring.
Redox Reactions: The compound can participate in various redox reactions, especially with strong oxidizing or reducing agents, leading to the formation of different oxidation states of the pyridine ring.
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