Chemistry Heterocyclic Building Blocks Pyrazoles 5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazole

5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazole

Aromatic Electrophilic Substitution: The aromatic rings in the structure can undergo electrophilic substitution reactions, where an electrophile replaces a hydrogen atom on the aromatic ring. Common electrophiles include halogens (e.g., bromination or chlorination) or nitration. Ring Opening: The compound may undergo ring-opening reactions under certain conditions. For example, if you treat it with a strong base, it can undergo ring-opening to form an open-chain compound. Cyclization Reactions: Depending on the functional groups present, it may undergo cyclization reactions to form other heterocyclic compounds or ring-fused structures. Reduction: The compound can be reduced to yield the corresponding saturated analog by using reducing agents such as hydrogen gas and a catalyst, or with reducing agents like sodium borohydride. Oxidation: Oxidation reactions can convert certain functional groups within the molecule. For example, you can oxidize a secondary amine to a ketone or aldehyde using oxidizing agents. Diazo Coupling: If you have diazonium salts, you can perform diazo coupling reactions with the compound. Rearrangement Reactions: Depending on the specific substituents and conditions, rearrangement reactions might be possible.

Further Reading:

Framework+−

(1-Methyl-1H-Pyrazol-3-Yl)Methanol (1-Phenyl-1H-Pyrazol-4-Yl)Boronic Acid 1,3-Dimethyl-1H-Pyrazole 1,3-Diphenyl-1H-Pyrazole 1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazole 1,5-Diphenyl-1H-Pyrazole 1-(2-Chlorophenyl)-1H-Pyrazole 1-(3-Chlorophenyl)-1H-Pyrazole 1-(4-Methoxybenzyl)-1H-Pyrazole 1-(Azetidin-3-Yl)-1H-Pyrazole 1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazole 1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazole 1-Benzyl-1H-Pyrazolo[3,4-B]Pyridine 1-Benzyl-4-Bromo-1H-Pyrazole 1-Benzyl-4-Iodo-1H-Pyrazole 1-Cyclopentyl-1H-Pyrazole 1-Cyclopropyl-1H-Pyrazole 1-Methyl-1H-Pyrazol-3-Amine 1-Methyl-3-Phenyl-1H-Pyrazole 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole 1-Methyl-5-Phenyl-1H-Pyrazole 1-Phenyl-1H-Pyrazol-3-Amine 1-Phenyl-1H-Pyrazol-3-Ol 1-Phenyl-1H-Pyrazol-5-Amine 1-Phenyl-1H-Pyrazole-3-Carboxylic Acid 1-Phenyl-1H-Pyrazole-4-Carbaldehyde 1-Phenyl-1H-Pyrazole-4-Carbonitrile 1-Phenyl-1H-Pyrazole-4-Carboxylic Acid 1-Phenyl-1H-Pyrazole-5-Carboxylic Acid 1-Phenyl-3-(Trifluoromethyl)-1H-Pyrazole 1-Trityl-1H-Pyrazole 1H-Pyrazol-4-Amine 1H-Pyrazol-4-Ol 1H-Pyrazol-5-Amine 1H-Pyrazole-4-Carbaldehyde 1H-Pyrazole-4-Carbonitrile 1H-Pyrazole-4-Carboxylic Acid 1H-Pyrazole-4-Sulfonyl Chloride 1H-Pyrazole-5-Carboxamide 1H-Pyrazole-5-Carboxylic Acid 1H-Pyrazolo[3,4-B]Pyrazine 1H-Pyrazolo[3,4-B]Pyridin-5-Amine 1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine 1H-Pyrazolo[4,3-D]Pyrimidine 2,3-Dihydropyrazolo[5,1-B]Oxazole 2,4-Dihydro-3H-Pyrazol-3-One 2,6-Di(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-1-Yl)Pyrimidine 2-(1H-Pyrazol-3-Yl)Pyridine 2-Phenyl-2,4-Dihydro-3H-Pyrazol-3-One 3-(Tert-Butyl)-1-Phenyl-1H-Pyrazole 3-Bromo-1-Methyl-1H-Pyrazole 3-Bromopyrazolo[1,5-A]Pyridine 3-Bromopyrazolo[1,5-A]Pyrimidine 3-Chloro-1-Methyl-1H-Pyrazole 3-Cyclopropyl-1H-Pyrazole 3-Iodo-1-Methyl-1H-Pyrazole 3-Iodo-1H-Pyrazolo[3,4-B]Pyridine 3-Methyl-1-Phenyl-1H-Pyrazole 3-Phenyl-1H-Pyrazol-5-Amine 4,5,6,7-Tetrahydro-1H-Pyrazolo[3,4-C]Pyridine 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridine 4-(1H-Pyrazol-1-Yl)Benzoic Acid 4-(1H-Pyrazol-1-Yl)Piperidine 4-Bromo-1-Methyl-1H-Pyrazole 4-Bromo-1-Phenyl-1H-Pyrazole 4-Bromo-1H-Pyrazolo[3,4-B]Pyridine 4-Bromopyrazolo[1,5-A]Pyridine 4-Chloro-1H-Pyrazole 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine 4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine 4-Iodo-1H-Pyrazole 4-Methyl-1-Phenyl-1H-Pyrazole 4-Methyl-1H-Pyrazole 4-Nitro-1H-Pyrazole 4-Phenyl-1H-Pyrazole 5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazole 5-(Difluoromethyl)-1H-Pyrazole 5-Bromo-1H-Pyrazole 5-Bromo-1H-Pyrazolo[3,4-B]Pyridine 5-Bromo-1H-Pyrazolo[3,4-C]Pyridine 5-Chloro-1H-Pyrazole 5-Chloro-1H-Pyrazolo[3,4-B]Pyridine 5-Chloropyrazolo[1,5-A]Pyrimidine 5-Cyclopropyl-1H-Pyrazole 5-Iodo-1H-Pyrazole 5-Nitro-1H-Pyrazole 5-Nitro-1H-Pyrazolo[3,4-B]Pyridine 5-Phenyl-1H-Pyrazole-3-Carboxylic Acid 6,7-Dihydro-5H-Pyrazolo[5,1-B][1,3]Oxazine 6-Bromopyrazolo[1,5-A]Pyridine 6-Bromopyrazolo[1,5-A]Pyrimidine 6-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine 7-Chloropyrazolo[1,5-A]Pyrimidine Ethyl 1-Phenyl-1H-Pyrazole-3-Carboxylate Ethyl 1-Phenyl-1H-Pyrazole-4-Carboxylate Ethyl 1H-Pyrazole-4-Carboxylate Ethyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Ethyl Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate Methyl 1H-Pyrazole-4-Carboxylate Methyl 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Pyrazolo[1,5-A]Pyrazine Pyrazolo[1,5-A]Pyridine-2-Carboxylic Acid Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid Tert-Butyl 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate Tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Carboxylate

By Key Group+−

Amino-Pyrazole-Carboxylate Amino-Pyrazolopyridine Aminopyrazolo Benzylpyrazol-Amide Bipyrazole Bromo-Methyl-Pyrazole Bromo-Pyrazol-Amide Bromo-Pyrazole-Carboxylate Bromo-Pyrazolopyridine Bromo-Pyrazolopyrimidine Bromo-Trifluoromethyl-Pyrazole Bromopyrazolo Chloro-Methyl-Pyrazole Chloro-Pyrazolamide Chloro-Pyrazole Chloro-Pyrazole-Carboxylate Chloro-Pyrazolopyridine Chloro-Pyrazolopyrimidine Chloropyrazolo Dichloropyrazolo Difluoromethyl-Pyrazole Difluoromethyl-Pyrazole-Carboxylate Dihydropyrazolo Dimethyl-Pyrazol-Amide Dimethyl-Pyrazole-Carboxylate Dimethyl-Pyrazole-Carboxylic Acid Dimethylpyrazole Dimethylpyrazolo Dioxaborolan-Pyrazole Ethyl-Pyrazol-Amide Ethylpyrazole Fluoropyrazolo Hydroxy-Pyrazole Hydroxy-Pyrazolopyrimidine Hydroxypyrazolo Iodo-Methyl-Pyrazole Iodo-Pyrazole-Carboxylate Iodopyrazolo Isopropyl-Pyrazol-Amide Methoxy-Pyrazolo-Pyridine Methoxypyrazolo Methy-Pyrazolooxazine Methyl-Hydrox-Ypyrazole Methyl-Nitro-Pyrazole Methyl-Pyrazol-One Methyl-Pyrazole-Carboxylic Acid Methyl-Pyrazole-Carboxylic-Acid Methyl-Pyrazolone Methyl-Pyrazolopyridine Methylpyrazole Methylpyrazolo Nitro-Pyrazole-Carboxylate Phenyl-Pyrazol-Amide Phenyl-Pyrazole-Carboxylate Phenyl-Pyrazolidine Phenylpyrazole Pyrazo-Morpholine Pyrazol-Amine Pyrazol-Boronic Acid Pyrazol-Methanol Pyrazol-One Pyrazol-Piperazine Pyrazol-Pyridine Pyrazole-Carbonitrile Pyrazole-Carboxylate Pyrazole-Carboxylic Acid Pyrazole-Ethanol Pyrazole-Hydrochloride Pyrazole-Methamine Pyrazole-Phenyl-Boronic-Acid Pyrazole-Piperidine Pyrazolo-Pyrimidine Pyrazolooxazine Pyrazolopyrazine Pyrazolopyridin-Ol Pyrazolopyridin-One Pyrazolopyridine Pyrazolopyridine-Carbonitrile Pyrazolopyridine-Carboxylate Pyrazolopyridine-Carboxylic Acid Pyrazolopyridine-Carboxylic-Acid Pyrazolopyridine-Methanol Pyrazolopyrimid-One Pyrazolopyrimidine Pyrazolotriazine Pyridine-Pyrazole Pyrimidine-Pyrazole Pyrrolopyrazole Tetrahydropyran-Pyrazole Tetrahydropyranopyrazole Tetrahydropyrazolo Trifluoromethyl-Phenyl-Pyrazol Trifluoromethyl-Pyrazol-Amide Trifluoromethyl-Pyrazole Trifluoromethyl-Pyrazolone

By Parent Nucleus+−

Aliphatic Heterocycles Aromatic Heterocycles Azetidines Furans Guanidines Imidazoles Indazoles Indoles Other Aliphatic Heterocycles Other Aromatic Heterocycles Oxetanes Piperazines Piperidines Pyrazines Pyridazines Pyridines Pyrimidines Pyrroles Pyrrolidines Quinolines Tetrahydrofurans Tetrahydropyrans Thiophenes

By Functional Group+−

Alcohols Aldehydes Aliphatic Chain Hydrocarbons Aliphatic Cyclic Hydrocarbons Alkenyls Alkyls Alkynyls Amides Amines Aryls Benzyl Bromides Benzyl Chlorides Bromides Carboxylic Acids Chiral Building Blocks Chlorides Difluoromethyls Esters Ethers Fluorinated Building Blocks Hydrazones Iodides Ketones Nitriles Nitroes Oximes Phenols Phosphoruses Sulfamides Sulfides Sulfonates Sulfonic Acids Sulfonyl Chlorides Trifluoromethyls Ureas

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    Ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate

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    Ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate

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    (5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)methanamine

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    5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid

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    5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid

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    Methyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate

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    Methyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate

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    3-Bromo-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole

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    3-Bromo-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole

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    5,5-Dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole

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    5,5-Dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole

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    5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid

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    5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid

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