Home Chemistry Heterocyclic Building Blocks Pyridines 6-Fluoropyridin-2-Amine
Substitution Reactions: The amino group in the compound can undergo substitution reactions with electrophiles, such as alkyl halides or acyl chlorides, leading to the formation of N-alkyl or N-acyl derivatives.
Acylation: The amino group can undergo acylation reactions with acyl chlorides or acid anhydrides, leading to the formation of amides.
Diazotization: The amino group can undergo diazotization reactions with nitrous acid, forming diazonium salts. These salts can further react with various nucleophiles to produce azo compounds.
Fluorination Reactions: The fluorine atom in the compound can participate in various fluorination reactions, such as nucleophilic fluorination or electrophilic fluorination, leading to the introduction of additional fluorine atoms or substitution of the existing fluorine atom.
Reduction Reactions: The amino group can undergo reduction reactions to form corresponding amines, such as using reducing agents like lithium aluminum hydride or hydrogenation catalysts like palladium on carbon.
Condensation Reactions: The amino group can undergo condensation reactions with carbonyl compounds, such as ketones or aldehydes, leading to the formation of imines or Schiff bases.
Heterocyclization Reactions: The amino group can participate in heterocyclization reactions, especially with carbonyl compounds or unsaturated systems, leading to the formation of heterocycles.
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