Home Chemistry Heterocyclic Building Blocks Pyridines 6-Methylnicotinic Acid
Esterification: 6-methylnicotinic acid can undergo esterification reactions with alcohols in the presence of an acid catalyst to form esters. The carboxylic acid group (-COOH) reacts with the hydroxyl group (-OH) of the alcohol to form an ester and water.
Amide Formation: It can react with amines to form amides. This reaction involves the replacement of the carboxylic acid group with an amino group (-NH2) from the amine.
Decarboxylation: Under certain conditions, such as heating with a suitable catalyst, 6-methylnicotinic acid can undergo decarboxylation, resulting in the removal of the carboxyl group (-COOH) to form methylpyridine.
Substitution Reactions: The methyl group in 6-methylnicotinic acid can undergo substitution reactions with various reagents, leading to the introduction of different functional groups at the methyl position.
Oxidation: It can be oxidized to form various products, depending on the conditions and reagents used. For example, oxidation with strong oxidizing agents can lead to the formation of carboxylic acids with additional functional groups.
Reduction: It can be reduced to form products with fewer oxygen atoms, such as alcohols or even hydrocarbons, depending on the reagents and conditions used for the reduction reaction.
Halogenation: Under certain conditions, 6-methylnicotinic acid can undergo halogenation reactions, where halogen atoms (such as chlorine, bromine, or iodine) can replace hydrogen atoms in the molecule.
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