Chemistry Heterocyclic Building Blocks Pyridines (3-methylpyridin-2-yl)methanamine
Ambeed provide 5 derivatives of (3-methylpyridin-2-yl)methanamine.
These compounds have the same murcko framework: (3-methylpyridin-2-yl)methanamineNucleophilic substitution: The amine group can act as a nucleophile, participating in reactions with electrophiles. For instance, it can react with alkyl halides or acyl halides to form substituted amines or amides, respectively.
Protonation: The amine group can accept a proton, becoming positively charged. This protonation can occur in acidic conditions, forming a more reactive species.
Reductive amination: The amine group can react with a carbonyl compound (such as an aldehyde or a ketone) in the presence of a reducing agent to form secondary or tertiary amines.
Condensation reactions: The amine group can undergo condensation reactions with carbonyl compounds to form imines or Schiff bases.
Cyclization reactions: The amine and pyridine functionalities can participate in cyclization reactions, leading to the formation of heterocyclic compounds.
Oxidation reactions: The amine group can undergo oxidation to form amine oxides or other oxidized products.
Metal complexation: The amine nitrogen and the pyridine nitrogen can both coordinate with transition metal ions to form metal complexes.
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(3-Methylpyridin-2-yl)methanamine dihydrochloride
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(3-Methylpyridin-2-yl)methanamine hydrochloride
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(4-Methoxy-3,5-dimethylpyridin-2-yl)methanamine dihydrochloride
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(3,5-Dimethylpyridin-2-yl)methanamine hydrochloride