Chemistry Heterocyclic Building Blocks Pyridines (4R,5S)-4,5-diphenyl-2-(pyridin-2-yl)-4,5-dihydrooxazole
Substitution Reactions: The compound contains a pyridine ring and an oxazole ring, both of which can undergo substitution reactions. For example, you can perform N-alkylation, N-acylation, or O-alkylation reactions to introduce new functional groups.
Reduction Reactions: The dihydrooxazole ring suggests the presence of double bonds that can be reduced to single bonds. Common reducing agents like hydrogen and a catalyst or metal hydrides can be used for this purpose.
Amination: You can introduce amino groups by performing reactions like reductive amination, where an amine is introduced by replacing another functional group.
Oxidation Reactions: Depending on the specific reaction conditions, you might be able to oxidize the compound to introduce new functional groups or increase its oxidation state.
Cross-Coupling Reactions: If the compound contains suitable leaving groups, you can perform cross-coupling reactions, such as Suzuki or Heck reactions, to form new carbon-carbon bonds.
Ring-Opening Reactions: If the oxazole ring can be opened under certain conditions, it can lead to the formation of new compounds with different functional groups.
Cyclization Reactions: You can perform intramolecular reactions to create new cyclic structures or rearrange the existing rings.
Chirality Control: The compound is chiral (4R,5S), so you can perform reactions that are stereospecific and manipulate the stereochemistry of the molecule.
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(3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methanol
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(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol hydrochloride
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2-(Hydroxymethyl)-3,5-dimethylpyridin-4-ol
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2-Hydroxymethyl-3-methyl-4-nitropyridine
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(4-Chloro-3,5-dimethylpyridin-2-yl)methanol
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(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol