Chemistry Heterocyclic Building Blocks Pyridines (3aR,8aS)-2-(pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
Ambeed provide 6 derivatives of (3aR,8aS)-2-(pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole.
These compounds have the same murcko framework: (3aR,8aS)-2-(pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole.
Substitution Reactions: The pyridine and oxazole rings can undergo various substitution reactions, such as electrophilic aromatic substitution, nucleophilic aromatic substitution, or metal-catalyzed coupling reactions.
Ring Opening: Depending on the conditions, the oxazole ring might be susceptible to ring-opening reactions. This could lead to the formation of open-chain compounds or the participation of the oxygen atom in other reactions.
Addition Reactions: The compound might undergo addition reactions with nucleophiles or electrophiles, depending on the nature of the compound it reacts with.
Rearrangement Reactions: Under specific conditions and with appropriate catalysts, rearrangement reactions may occur, leading to the formation of different isomeric products.
Hydrolysis: If exposed to strong acids or bases, the compound could undergo hydrolysis reactions, resulting in the cleavage of chemical bonds and formation of new compounds.
Reduction: It may undergo reduction reactions, depending on the reducing agents and conditions used. This could result in the saturation of some double bonds or the reduction of functional groups.
Oxidation: Oxidizing agents might lead to the oxidation of specific functional groups within the compound.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
(3AR,8aS)-2-(5-(trifluoromethyl)pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
click to sign in and save
(3aR,8aS)-2-(Pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
click to sign in and save
(3aR,8aS)-2-(4-(Trifluoromethyl)pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
click to sign in and save
(3aR,8aS)-2-(5-Chloropyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
click to sign in and save
(3aR,8aS)-2-(5-Bromopyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
click to sign in and save
(3aR,8aS)-2-(6-Methylpyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole