Chemistry Heterocyclic Building Blocks Oxazolines (3aS,8aR)-2-(pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
Ambeed provide 7 derivatives of (3aS,8aR)-2-(pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole.
These compounds have the same murcko framework: (3aS,8aR)-2-(pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole.
Substitution Reactions: If there are reactive sites like halogens, amines, or other leaving groups, they can be replaced by other functional groups or atoms.
Addition Reactions: If the compound contains unsaturated bonds (e.g., double or triple bonds), it might undergo addition reactions, where atoms or groups are added to these unsaturated sites.
Oxidation/Reduction Reactions: Depending on the presence of electron-rich or deficient regions, the compound may be susceptible to oxidation or reduction reactions.
Acid-Base Reactions: If the compound contains acidic or basic groups, it may react with appropriate acids or bases.
Photochemical Reactions: Some compounds are sensitive to light and can undergo reactions when exposed to certain wavelengths.
Complexation Reactions: Depending on the presence of metal-binding sites, the compound may form complexes with metal ions.
Polymerization Reactions: If the compound contains reactive sites, it might be able to undergo polymerization reactions.
Hydrolysis Reactions: If there are susceptible bonds (like esters, amides, etc.), they might undergo hydrolysis in the presence of water.
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(3aS,8aR)-2-(5-(Trifluoromethyl)pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
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(3aS,8aR)-2-(Pyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole
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(3aS,8aR)-2-(4-(Trifluoromethyl)pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
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(3aS,8aR)-2-(5-Bromopyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
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(3aS,8aR)-2-(6-Methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
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(3aS,8aR)-2-(5-Chloropyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
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(3AS,8aR)-2-(4-methoxy-6-methylpyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole