Chemistry Heterocyclic Building Blocks Pyridines (5-chloropyridin-2-yl)methanamine
Ambeed provide 5 derivatives of (5-chloropyridin-2-yl)methanamine.
These compounds have the same murcko framework: (5-chloropyridin-2-yl)methanamineUcleophilic substitution: The amine group can act as a nucleophile and undergo substitution reactions with electrophiles. For instance, it can react with alkyl halides to form N-alkylated products.
Condensation reactions: The amine group can participate in condensation reactions with carbonyl compounds (such as aldehydes and ketones) to form imines or Schiff bases.
Acylation: The amine group can undergo acylation reactions with acyl chlorides or acid anhydrides to form amides.
Ring-closure reactions: The compound contains a chloropyridine moiety, which can undergo various ring-closure reactions under appropriate conditions.
Reduction: The compound may undergo reduction reactions, converting the chloropyridine group to a different functional group.
Substitution reactions: The chlorine atom in the chloropyridine group can undergo substitution reactions with appropriate nucleophiles.
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(5-Chloro-3-methylpyridin-2-yl)methanamine hydrochloride
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(5-Chloropyridin-2-yl)methanamine hydrochloride
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(5-Chloropyridin-2-yl)methanamine dihydrochloride
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(5-Chloro-3-fluoropyridin-2-yl)methanamine hydrochloride