Chemistry Heterocyclic Building Blocks Indolines (Z)-3-(phenyl(phenylamino)methylene)indolin-2-one
Hydrolysis: The Schiff base can undergo hydrolysis in the presence of acid or base to yield the corresponding amine and ketone.
Reduction: The imine group can be reduced to the corresponding amine using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
Mannich Reaction: The compound can react with amines and formaldehyde to form Mannich adducts, which are β-amino carbonyl compounds.
Condensation Reactions: It can participate in condensation reactions with various nucleophiles, including alcohols and amines, to form new carbon-nitrogen or carbon-oxygen bonds.
Acylation: The carbonyl group can undergo acylation reactions with acyl chlorides or anhydrides to form amides.
Oxidation: The compound can be oxidized to form indole derivatives or other products, depending on the reaction conditions and reagents used.
Reductive Amination: The Schiff base can be used as a starting material for reductive amination reactions, where it reacts with an amine and a reducing agent to form secondary or tertiary amines.
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