Chemistry Heterocyclic Building Blocks Imidazoles 1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

Ambeed provide 11 derivatives of 1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole.

These compounds have the same murcko framework: 1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole.

Arylation: DPh-BIM contains two phenyl groups, which are electron-rich aromatic rings. These phenyl groups can undergo various arylation reactions, such as Suzuki coupling, Stille coupling, or Heck reaction, to introduce different aryl substituents at the phenyl positions.
Halogenation: DPh-BIM can undergo halogenation reactions, such as bromination or chlorination, at the aromatic rings or other suitable positions. These reactions are often carried out using halogenating agents like N-bromosuccinimide (NBS) or chlorine gas.
N-alkylation: The nitrogen atoms in the imidazole rings can undergo N-alkylation reactions with alkyl halides or alkylating agents to introduce alkyl groups onto the imidazole nitrogen atoms.
Dehydration: In the presence of strong acids or high-temperature conditions, DPh-BIM may undergo dehydration reactions to form aromatic compounds with fewer hydrogen atoms.
Cyclization: DPh-BIM contains two imidazole rings, and under specific conditions, it may undergo intramolecular cyclization reactions to form fused-ring compounds.
Metal Complexation: The imidazole nitrogen atoms can coordinate with metal ions to form metal complexes. This property can be used in various catalytic reactions.
Cross-Coupling Reactions: DPh-BIM can participate in cross-coupling reactions with other organic compounds or reagents, leading to the formation of diverse products.

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Conditions to empty

Framework+−

1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole 1,2-dimethyl-1H-imidazole 1,3-diphenyl-1H-imidazol-3-ium 1,3-diphenyl-4,5-dihydro-1H-imidazol-3-ium 1-(imidazo[1,2-a]pyridin-3-yl)ethan-1-one 1-(phenylsulfonyl)-1H-imidazole 1-benzyl-1H-imidazole 1-decyl-3-methyl-1H-imidazol-3-ium 1-ethyl-1H-imidazole 1-isopropyl-1H-imidazole 1-phenyl-1H-imidazole-4-carboxylic acid 1-trityl-1H-imidazole 1H-imidazo[4,5-b]pyridine 1H-imidazo[4,5-c]pyridine 1H-imidazol-2-amine 1H-imidazole-2-carboxylic acid 1H-imidazole-4-carbonitrile 1H-imidazole-4-carboxylic acid 2-(pyridin-2-yl)-1H-benzo[d]imidazole 2-bromo-1H-imidazole 2-bromoimidazo[1,2-a]pyridine 2-ethyl-1H-imidazole 2-methyl-1-phenyl-1H-imidazole 2-methylimidazo[1,2-a]pyridine 2-phenyl-1H-benzo[d]imidazole 2-phenyl-1H-imidazole 2-phenylimidazo[1,2-a]pyridine 2-propyl-1H-imidazole 3-bromoimidazo[1,2-a]pyrazine 3-bromoimidazo[1,2-a]pyridine 3-bromoimidazo[1,2-a]pyrimidine 3-iodoimidazo[1,2-a]pyridine 3-methylimidazo[1,2-a]pyridine 4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine 4-(1H-imidazol-1-yl)benzaldehyde 4-bromo-1-phenyl-1H-imidazole 4-methyl-1-phenyl-1H-imidazole 4-methyl-1H-imidazole 4-phenyl-1H-imidazole 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine 5-benzyl-1H-imidazole 5-bromoimidazo[1,2-a]pyridine 5-chloro-1H-imidazole 5-fluoro-1H-benzo[d]imidazole 5-iodo-1H-imidazole 5-methylimidazo[1,2-a]pyridine 5-phenyl-1H-imidazole 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole 6-bromoimidazo[1,2-a]pyrazine 6-bromoimidazo[1,2-a]pyridine 6-bromoimidazo[1,2-a]pyrimidine 6-chloroimidazo[1,2-a]pyridine 6-chloroimidazo[1,2-b]pyridazine 7-methylimidazo[1,2-a]pyridine 8-bromoimidazo[1,2-a]pyrazine 8-bromoimidazo[1,2-a]pyridine 8-chloroimidazo[1,2-a]pyrazine 8-chloroimidazo[1,2-a]pyridine 8-fluoroimidazo[1,2-a]pyridine 8-methylimidazo[1,2-a]pyridine ethyl 1H-imidazole-2-carboxylate ethyl 2-(imidazo[1,2-a]pyridin-3-yl)acetate ethyl imidazo[1,2-a]pyridine-2-carboxylate ethyl imidazo[1,2-a]pyridine-3-carboxylate imidazo[1,2-a]pyridin-3-amine imidazo[1,2-a]pyridin-8-amine imidazo[1,2-a]pyridin-8-ol imidazo[1,2-a]pyridine-2-carbaldehyde imidazo[1,2-a]pyridine-2-carboxylic acid imidazo[1,2-a]pyridine-3-carbaldehyde imidazo[1,2-a]pyridine-3-carboxylic acid imidazo[1,2-a]pyridine-7-carboxylic acid imidazo[1,2-a]pyridine-8-carboxylic acid imidazo[1,2-a]pyrimidine-3-carboxylic acid imidazo[1,2-c]pyrimidine imidazo[1,5-a]pyrazine imidazo[2,1-b]thiazole methyl 1H-imidazole-2-carboxylate methyl 1H-imidazole-5-carboxylate methyl imidazo[1,2-a]pyridine-8-carboxylate tert-butyl 1H-imidazole-1-carboxylate

By Key Group+−

aminoimidazole-carboxylate benzyl-imidazole benzyl-methyl-imidazole biimidazole bromo-imidazole bromo-imidazopyridine bromo-methyl-imidazole bromoimidazo bromoimidazole carboxylate chloro-imidazopyridine chloroimidazo dibromoimidazo dichloroimidazo dihydroimidazo dimethyl-imidazol dimethylimidazo dimethylimidazolium dioxaborolane-imidazole ethyl-imidazole fluoroimidazo hydroxy-imidazopyridine imidazol-amine imidazol-ethanol imidazol-hydrochloride imidazol-ium imidazol-methanamine imidazol-methanol imidazol-nitrile imidazol-pyridine imidazole-carboxylate imidazole-carboxylic acid imidazolyl-pyrimidine imidazopyrazine imidazopyridazine imidazopyridin-amine imidazopyridin-one imidazopyridine imidazopyridine-carbonitrile imidazopyridine-carboxylate imidazopyridine-carboxylic acid imidazopyrimidine imidazoquinoline imidazothiazole iodoimidazo iodomethyl-imidazole isopropyl-imidazole methoxyimidazo methyl-imidazopyridine methyl-nitro-imidazole methylimidazo methylimidazole methylimidazolium nitro-imidazole-carboxylate nitroimidazole phenylimidazo phenylimidazole piperidin-imidazolyl pyrroloimidazole tetrahydroimidazo thienoimidazol trifluoromethyl-imidazo trifluoromethyl-imidazole trifluoromethyl-imidazopyridine

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Aliphatic Heterocycles Aromatic Heterocycles Dioxolanes Indazoles Other Aliphatic Heterocycles Other Aromatic Heterocycles Piperazines Piperidines Pyrazines Pyrazoles Pyridines Pyrimidines Pyrrolidines Spiroes Tetrahydropyrans Thiophenes Thiophenols Triazines Triazoles

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    By Configuration+−

    (4S,4'S)-4,4'-Diisopropyl-1,1'-bis(4-(trifluoromethyl)phenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011752374958-84-497%

    (4S,4'S)-4,4'-Diisopropyl-1,1'-bis(4-(trifluoromethyl)phenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $265.00/250mg

    Detail
    (4S,4'S)-1,1'-Bis(3-(tert-butyl)phenyl)-4,4'-diisopropyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011732374958-80-097%

    (4S,4'S)-1,1'-Bis(3-(tert-butyl)phenyl)-4,4'-diisopropyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $241.00/250mg

    Detail
    (4S,4'S)-4,4'-Diisobutyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15979782828444-14-895%

    (4S,4'S)-4,4'-Diisobutyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $241.00/250mg

    Detail
    (4S,4'S)-4,4'-Di-tert-butyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011821827669-27-197%

    (4S,4'S)-4,4'-Di-tert-butyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $718.00/1g

    Detail
    (4S,4'S)-4,4'-Diisopropyl-1,1'-bis(3-isopropylphenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011722374958-79-797%

    (4S,4'S)-4,4'-Diisopropyl-1,1'-bis(3-isopropylphenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $129.00/100mg

    Detail
    (4S,4'S)-4,4'-Diisopropyl-1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A14738032374958-82-297%

    (4S,4'S)-4,4'-Diisopropyl-1,1'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $241.00/250mg

    Detail
    (4S,4'S)-4,4'-Diisopropyl-1,1'-di-m-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011712374958-85-597%

    (4S,4'S)-4,4'-Diisopropyl-1,1'-di-m-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $145.00/50mg

    Detail
    (4S,4'S)-1,1'-Bis(3-(tert-butyl)phenyl)-4,4'-diisobutyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15431112828440-25-995%

    (4S,4'S)-1,1'-Bis(3-(tert-butyl)phenyl)-4,4'-diisobutyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $131.00/100mg

    Detail
    (4S,4'S)-4,4'-Diisopropyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011701827669-26-097%

    (4S,4'S)-4,4'-Diisopropyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $110.00/100mg

    Detail
    (4S,4'S)-4,4'-Diisopropyl-1,1'-bis(4-methoxyphenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15011742374958-83-397%

    (4S,4'S)-4,4'-Diisopropyl-1,1'-bis(4-methoxyphenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $790.00/1g

    Detail
    (4S,4'S)-4,4'-Diisobutyl-1,1'-bis(3-isopropylphenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

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    A15431092828440-24-895%

    (4S,4'S)-4,4'-Diisobutyl-1,1'-bis(3-isopropylphenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole

    $824.00/1g

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