Chemistry Organic Building Blocks Fluorinated Building Blocks 1,2-difluoro-3-methylbenzene
Ambeed provide 23 derivatives of 1,2-difluoro-3-methylbenzene.
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH3).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Halogenation: Toluene can undergo halogenation reactions with halogens (such as chlorine or bromine) in the presence of a catalyst or under UV light. The hydrogen atoms on the benzene ring can be replaced by halogen atoms, resulting in the formation of mono-, di-, or polyhalogenated derivatives of toluene.
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1-Bromo-2,4,5-trifluoro-3-methylbenzene
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(2,3-Difluoro-4-methylphenyl)boronic acid
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(3,4-Difluoro-2-methylphenyl)methanamine hydrochloride
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2,3,5,6-Tetrafluoro-4-methylbenzyl Alcohol
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(3,4-Difluoro-2-methylphenyl)boronic acid