Chemistry
Organic Building Blocks
Bromides
1,3-dibromo-2-chlorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—Cl).
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
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1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene