Ambeed provide 5 derivatives of 1,3-dichloro-2-iodobenzene.
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—Cl).
Metalation Reactions: Iodobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
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