Chemistry Heterocyclic Building Blocks Pyridines 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Ambeed provide 19 derivatives of 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one.
These compounds have the same murcko framework: 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one.
Electrophilic Aromatic Substitution (SEAr): Depending on the substituents attached to the ring, this compound might undergo electrophilic aromatic substitution reactions. For instance, if there are electron-donating groups, they can activate the ring towards electrophilic attack.
Aldol Condensation: If there are suitable functional groups present, 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one can participate in aldol condensation reactions. This would involve the formation of a C-C bond.
Reduction: The double bond in the pyrrolo[2,3-b]pyridin-2-one ring can potentially be reduced to a single bond using reducing agents.
Oxidation: Depending on the conditions and substituents, the compound may be susceptible to oxidation reactions, potentially leading to the formation of various products.
Ring Opening Reactions: Depending on the conditions and substituents, the ring can potentially undergo ring-opening reactions, leading to the formation of acyclic compounds.
Cyclization Reactions: Depending on the reactants and conditions, the compound may undergo cyclization reactions to form other cyclic compounds.
Rearrangements: Depending on the specific structure and conditions, rearrangement reactions could occur.
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5-Chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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2-oxo-2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
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1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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4,6-Dichloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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3,3-Dibromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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3,3,5-Tribromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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4-Bromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
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6-Bromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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4-Chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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5-Bromo-1,3,3-trimethyl-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
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3-Methyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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6-Chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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5-Hydroxy-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
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6-Chloro-3,3-dimethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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5-Bromo-3,3-dimethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
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5-Bromo-6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one