Chemistry Heterocyclic Building Blocks Pyrazoles 1,3-diphenyl-1H-pyrazole
Acylation: 1,3-diphenyl-1H-pyrazole can undergo acylation reactions, where an acyl group (such as an acetyl group) is added to the nitrogen atom in the pyrazole ring.
Alkylation: The compound can be alkylated by the addition of alkyl groups to the nitrogen atom in the pyrazole ring. This can be done using alkyl halides or similar reagents.
Reduction: Reduction reactions can be carried out to reduce any functional groups present in the molecule, such as reducing a carbonyl group to an alcohol or a nitro group to an amine.
Oxidation: Oxidation reactions can be performed to convert functional groups within the molecule. For example, oxidation of an alcohol group to a ketone or carboxylic acid.
Substitution reactions: Depending on the reaction conditions and reagents used, various substitution reactions can occur, where functional groups are replaced with other groups. For example, the halogenation of aromatic rings or the substitution of one of the phenyl groups.
Condensation reactions: 1,3-diphenyl-1H-pyrazole can participate in condensation reactions to form larger molecules. For instance, it can be involved in the synthesis of heterocyclic compounds by reacting with other suitable reagents.
Metal-catalyzed reactions: Metal-catalyzed reactions, such as metal-catalyzed cross-coupling reactions, can be employed to functionalize the pyrazole ring or one of the phenyl groups.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-5-amine
click to sign in and save
1-Phenyl-3-(p-tolyl)-1H-pyrazole-4-carbaldehyde
click to sign in and save
Ethyl 1,3-diphenyl-1H-pyrazole-5-carboxylate