Chemistry Organic Building Blocks Iodides 1,4-dibromo-2-iodobenzene
Ambeed provide 3 derivatives of 1,4-dibromo-2-iodobenzene.
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—Br).
Cross-Coupling Reactions: Iodobenzene is commonly used in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling an aryl halide (like iodobenzene) with an organometallic reagent, leading to the formation of new carbon-carbon bonds.
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal alkynes using a palladium catalyst, leading to the formation of substituted alkynes.
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