1-(2-fluorophenyl)propan-1-amine-Sulfones| Ambeed

Chemistry Organic Building Blocks Fluorinated Building Blocks 1-(2-fluorophenyl)propan-1-amine

1-(2-fluorophenyl)propan-1-amine

Ambeed provide 1 derivatives of 1-(2-fluorophenyl)propan-1-amine.

These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH(NH₂)CH₂CH₃).

Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Acid-Base Reactions: 1-phenylpropan-1-amine is a weak base due to the lone pair of electrons on the nitrogen atom. It can undergo acid-base reactions with acids to form salts. Acylation: 1-phenylpropan-1-amine can undergo acylation reactions, where an acyl group (usually a carbonyl compound) is introduced onto the amine group. This can be achieved using acyl chlorides or anhydrides in the presence of a base. The specific product will depend on the choice of reagents. Substitution Reactions: The phenyl group in 1-phenylpropan-1-amine can undergo various substitution reactions. For instance, it can undergo electrophilic aromatic substitution reactions if the conditions are appropriate.

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