Chemistry Heterocyclic Building Blocks Pyridines 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
Ambeed provide 30 derivatives of 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine.
These compounds have the same murcko framework: 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine.
Substitution Reactions: The phenylsulfonyl group (-SO2Ph) is susceptible to nucleophilic substitution reactions. For example, it can be replaced by various nucleophiles like amines, alcohols, or thiols.
Arylation Reactions: The phenyl ring can undergo various arylation reactions, such as Suzuki, Heck, or Sonogashira coupling, which can lead to the introduction of various substituents on the phenyl ring.
Cyclization Reactions: Depending on the reaction conditions, the compound can undergo intramolecular cyclization reactions, forming cyclic compounds.
Reduction Reactions: The compound may undergo reduction reactions, for example, the reduction of the sulfonyl group to the sulfide, or the reduction of the pyridine or pyrrole rings.
Oxidation Reactions: Conversely, oxidation reactions can introduce oxygen-containing functional groups.
Nucleophilic Addition Reactions: Depending on the reactivity of the compound, it may undergo nucleophilic additions to various sites on the molecule.
Rearrangement Reactions: Under certain conditions, rearrangement reactions may occur, leading to isomer formation.
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4-Chloro-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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(1-Tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)boronic acid
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3-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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6-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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2-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
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4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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(4-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)boronic acid
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5-Bromo-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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4-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine
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4-Bromo-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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2-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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4-Chloro-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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6-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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1-((4-Methoxyphenyl)sulfonyl)-1H-pyrrolo[2,3-b]pyridine
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(1-Tosyl-1H-pyrrolo[2,3-b]pyridin-2-yl)boronic acid
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5-Chloro-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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4-Chloro-1-tosyl-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
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3-Bromo-4-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
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2-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine
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1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde
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4-Chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine
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4-Chloro-5-nitro-1-tosyl-1H-pyrrolo[2,3-b]pyridine
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5-Bromo-1-tosyl-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
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4-Bromo-2-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine
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2-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine