Chemistry Heterocyclic Building Blocks Pyrans thiochroman-4-one
Oxidation: The ketone group in thiochroman-4-one can be oxidized to form a carboxylic acid or other oxidation products. This can be achieved using oxidizing agents like potassium permanganate (KMnO4) or chromic acid (H2CrO4).
Reduction: The ketone group can be reduced to form a secondary alcohol. This can be accomplished using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
Nucleophilic Addition: The ketone carbon is electrophilic, making it susceptible to attack by nucleophiles. This can lead to the formation of addition products.
Substitution Reactions: The thiol group can potentially undergo substitution reactions, where the sulfur atom is replaced by another atom or group.
Ring-Opening Reactions: Depending on the reaction conditions and reagents used, the thiochroman-4-one ring can potentially open, leading to the formation of open-chain products.
Base-Catalyzed Reactions: The thiol group can also undergo base-catalyzed reactions, such as nucleophilic substitution reactions.
Metal Complexation: The sulfur atom can coordinate with transition metals, forming metal complexes.
Cyclization Reactions: Depending on the reaction conditions and reagents used, thiochroman-4-one can undergo cyclization reactions to form other heterocyclic compounds.
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(3-Bromo-4,5-dimethylphenyl)boronic acid
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1,2-Dibromo-4-methoxy-3,5,6-trimethylbenzene