Chemistry Organic Building Blocks Fluorinated Building Blocks 1-fluoro-3-methylbenzene
Ambeed provide 255 derivatives of 1-fluoro-3-methylbenzene.
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH3).
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Alkylation: Similar to acylation, toluene can also undergo Friedel-Crafts alkylation reactions, where an alkyl group is introduced onto the benzene ring. Alkylation reactions also require a Lewis acid catalyst.
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2-Fluoro-4-methylbenzenesulfinic acid sodium salt
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(2-Fluoro-4-methylphenyl)hydrazine hydrochloride
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Methyl 6-fluoro-2-methyl-3-nitrobenzoate
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2-(3-Chloro-4-fluoro-2-methylphenyl)acetic acid
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2-Chloro-1-fluoro-4-iodo-3-methylbenzene
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1-Chloro-4-fluoro-2-methyl-5-nitrobenzene
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Methyl 3-amino-4-fluoro-2-methylbenzoate
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(3,4-Difluoro-2-methylphenyl)boronic acid
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(4-Fluoro-2,6-dimethylphenyl)boronic acid
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Methyl 2-chloro-5-fluoro-3-methylbenzoate
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1-Fluoro-3-isothiocyanato-5-methylbenzene
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(3-Bromo-2-fluoro-4-methylphenyl)boronic acid
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1-Bromo-2-chloro-5-fluoro-3-methylbenzene