Chemistry Heterocyclic Building Blocks Tetrahydrofurans dihydrofuran-3(2H)-one

dihydrofuran-3(2H)-one

Hydrolysis: Gamma-butyrolactone can undergo hydrolysis in the presence of an acid or base to form gamma-hydroxybutyric acid (GHB). This reaction is often used for the synthesis of GHB, a psychoactive compound. Esterification: Gamma-butyrolactone can react with alcohols in the presence of acid catalysts to form esters. For example, it can be converted to gamma-butyrolactone acetate by reacting with acetic acid. Reduction: Dihydrofuran-3(2H)-one can be reduced to 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid (GHB), using reducing agents like sodium borohydride or lithium aluminum hydride. Dehydration: Under certain conditions, dihydrofuran-3(2H)-one can undergo dehydration to form crotonolactone, which is a cyclic ester. Oxidation: Gamma-butyrolactone can be oxidized to produce succinic acid under appropriate conditions, typically with strong oxidizing agents. Ring-opening reactions: The lactone ring in gamma-butyrolactone can be opened through nucleophilic attacks, leading to the formation of various compounds. Polymerization: Under specific conditions, gamma-butyrolactone can undergo polymerization reactions, forming larger molecules with multiple lactone rings.

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(2R,3S)-2-((benzoyloxy)methyl)tetrahydrofuran-3-yl benzoate (3aR,6aR)-hexahydrofuro[3,2-b]furan (3aS,6aS)-tetrahydrofuro[3,4-d][1,3]dioxole (R)-7-(tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine (R)-N-(9-(tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (tetrahydrofuran-2-yl)methanamine (tetrahydrofuran-2-yl)methanol (tetrahydrofuran-3-yl)methanamine 1,3-dihydrobenzo[c][1,2]oxaborole 1-(3-fluorotetrahydrofuran-2-yl)pyrimidin-2(1H)-one 1-(5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 1-(tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 1-oxa-8-azaspiro[4.5]decane 2-(acetoxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 2-(hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol 2-oxa-8-azaspiro[4.5]decane 2-oxabicyclo[2.1.1]hexane 3-aminodihydrofuran-2(3H)-one 3-iodotetrahydrofuran 4-amino-1-(tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 4-fluoro-2-(hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3-ol 4-hydroxydihydrofuran-2(3H)-one 5-(hydroxymethyl)dihydrofuran-2(3H)-one 5-bromo-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 5-oxotetrahydrofuran-2-carboxylic acid 9-(tetrahydrofuran-2-yl)-9H-purin-6-amine 9-(tetrahydrofuran-2-yl)-9H-purin-6-ol 9-(tetrahydrofuran-2-yl)-9H-purine dihydrofuran-3(2H)-one tert-butyl (tetrahydrofuran-3-yl)carbamate tetrahydrofuran-2-carboxylic acid tetrahydrofuran-3-amine tetrahydrofuran-3-carboxylic acid tetrahydrofuran-3-ol

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aminotetrahydrofuran dihydroxy-tetrahydrofuran dihydroxytetrahydrofuran methyltetrahydrofuran tetrahydrofuran-amine tetrahydrofuran-carboxylate tetrahydrofuran-carboxylic-acid tetrahydrofuran-diol tetrahydrofuran-hydrochloride tetrahydrofuran-methanol tetrahydrofuran-methylamine tetrahydrofuran-pyrimidine

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