1-phenylimidazolidin-2-one-Imidazolidines| Ambeed

Chemistry Heterocyclic Building Blocks Imidazolidines 1-phenylimidazolidin-2-one

1-phenylimidazolidin-2-one

Ambeed provide 8 derivatives of 1-phenylimidazolidin-2-one.

These compounds have the same murcko framework: 1-phenylimidazolidin-2-one.

Acid-Base Reactions: Phenytoin contains both acidic and basic functional groups. It can react with strong acids to form phenytoin salts, or with strong bases to form phenytoin bases.
Oxidation and Reduction Reactions: Phenytoin can be oxidized to its corresponding hydantoin derivative. This reaction may be carried out using various oxidizing agents.
Nucleophilic Substitution Reactions: Phenytoin contains a reactive carbonyl group, which can undergo nucleophilic addition reactions. For example, it can react with nucleophiles like amines to form substituted phenytoin derivatives.
Hoffmann Elimination: Under certain conditions, phenytoin can undergo a Hofmann elimination reaction to yield a substituted hydantoin derivative.
Ring Opening Reactions: The imidazolidinone ring in phenytoin can be cleaved under specific conditions, leading to the formation of products with an open ring structure.
Hydrolysis: Phenytoin is susceptible to hydrolysis under acidic or basic conditions, leading to the formation of various degradation products.
Photodegradation: Exposure to light, especially ultraviolet light, can lead to photodegradation of phenytoin. This can result in the formation of various photoproducts.
Metal Complexation Reactions: Phenytoin can form complexes with various metal ions, leading to changes in its chemical properties.