Chemistry Heterocyclic Building Blocks Pyridines 2,3,5-trichloropyridine
Ambeed provide 13 derivatives of 2,3,5-trichloropyridine.
These compounds have the same murcko framework: 2,3,5-trichloropyridineSubstitution Reactions: The chlorine atoms on the pyridine ring make it susceptible to substitution reactions where one or more of the chlorine atoms are replaced by other functional groups or atoms. These substitutions can lead to the formation of a wide range of derivatives.
Nucleophilic Substitution: Nucleophiles can attack the electron-deficient carbon atoms in the pyridine ring, leading to the substitution of chlorine atoms. This reaction is common in organic synthesis.
Electrophilic Substitution: The electron-rich nature of the pyridine ring can make it susceptible to attack by electrophiles, leading to the substitution of chlorine atoms. This reaction is typical for aromatic compounds.
Metalation Reactions: 2,3,5-trichloropyridine can react with strong bases or metals to form metal complexes or undergo metalation reactions where a metal atom is inserted into the pyridine ring.
Oxidation and Reduction Reactions: The chlorine atoms in 2,3,5-trichloropyridine can be subject to oxidation or reduction reactions, leading to the formation of products with different oxidation states.
Functional Group Transformations: By reacting 2,3,5-trichloropyridine with appropriate reagents, functional groups can be introduced, modified, or removed from the molecule, leading to the synthesis of various organic compounds.
Condensation Reactions: 2,3,5-trichloropyridine can participate in condensation reactions with other compounds, leading to the formation of larger molecules or polymers.
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