Chemistry Heterocyclic Building Blocks Pyridines 2,3-dihydro-1H-pyrrolo[2,3-c]pyridine
Ambeed provide 5 derivatives of 2,3-dihydro-1H-pyrrolo[2,3-c]pyridine.
These compounds have the same murcko framework: 2,3-dihydro-1H-pyrrolo[2,3-c]pyridine.
Aromatic Substitution: If there are suitable substituents on the aromatic ring of the compound, it can undergo electrophilic aromatic substitution reactions. For example, it can react with electrophiles (e.g., halogens, nitration reagents) to replace hydrogen atoms on the aromatic ring.
Nucleophilic Substitution: Depending on the functional groups present, it may undergo nucleophilic substitution reactions. For example, if there is a leaving group, the compound can undergo SN1 or SN2 reactions.
Ring Opening Reactions: Bicyclic compounds like 2,3-dihydro-1H-pyrrolo[2,3-c]pyridine can undergo ring-opening reactions under specific conditions, such as in the presence of strong nucleophiles or acids.
Oxidation and Reduction Reactions: The compound can undergo oxidation or reduction reactions depending on the reaction conditions. For example, it can be oxidized to form an N-oxide or reduced to form the corresponding dihydropyrrolopyridine.
Cycloaddition Reactions: It may participate in cycloaddition reactions, such as Diels-Alder reactions, to form fused ring systems.
Alkylation and Acylation: The compound can react with alkyl halides or acyl halides to introduce alkyl or acyl groups onto the molecule.
N-Heterocyclic Carbene Formation: It can be used as a precursor for the generation of N-heterocyclic carbenes, which are important ligands in organometallic chemistry.
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2,3-Dihydro-1H-pyrrolo[2,3-c]pyridine hydrochloride
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7-Chloro-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine
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5-Chloro-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine
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5-(Trifluoromethyl)-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine