Chemistry Heterocyclic Building Blocks Pyridines 2,3-dimethoxypyridine
Ambeed provide 7 derivatives of 2,3-dimethoxypyridine.
These compounds have the same murcko framework: 2,3-dimethoxypyridineNucleophilic substitution: The methoxy groups (-OCH3) can undergo nucleophilic substitution reactions at the 2 and 3 positions of the pyridine ring.
Acylation: The pyridine nitrogen can act as a nucleophile in acylation reactions, where it can react with acyl halides or anhydrides to form amides.
Alkylation: The nitrogen atom of the pyridine ring can also undergo alkylation reactions, reacting with alkyl halides or alkylating agents.
Oxidation: The electron-rich nature of the pyridine ring can make it susceptible to oxidation reactions under appropriate conditions.
Reduction: Conversely, the functional groups present in 2,3-dimethoxypyridine can also undergo reduction reactions, depending on the reagents and conditions used.
Condensation reactions: The pyridine nitrogen can participate in condensation reactions with carbonyl compounds or other suitable reactants to form various heterocyclic compounds.
Lewis acid-base reactions: The pyridine nitrogen can act as a Lewis base, forming complexes with Lewis acids.
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(5,6-Dimethoxypyridin-3-yl)boronic acid