Chemistry Heterocyclic Building Blocks Pyridines 2,3-dimethylpyridine
Ambeed provide 8 derivatives of 2,3-dimethylpyridine.
These compounds have the same murcko framework: 2,3-dimethylpyridineNucleophilic substitution: The nitrogen atom in the pyridine ring can undergo substitution reactions with electrophiles. For example, it can react with alkyl halides to form N-alkylated or N-acylated products.
Acylation reactions: 2,3-dimethylpyridine can react with acyl chlorides or acid anhydrides to form N-acyl derivatives.
Oxidation reactions: The methyl groups on the pyridine ring can undergo oxidation under appropriate conditions to give rise to corresponding aldehydes, ketones, or carboxylic acids.
Metalation reactions: The nitrogen atom in the pyridine ring can coordinate with transition metals to form metal complexes.
Alkylation reactions: Under certain conditions, the methyl groups can be replaced with other alkyl groups through alkylation reactions.
Ring-closure reactions: Depending on the reaction conditions and reagents used, 2,3-dimethylpyridine can undergo cyclization reactions to form various heterocyclic compounds.
Reduction reactions: The pyridine ring can be reduced to piperidine under appropriate conditions.
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2,3-Dimethylisonicotinic acid hydrochloride