Chemistry Heterocyclic Building Blocks Pyridines 2,4,6-trichloropyridine
Ambeed provide 5 derivatives of 2,4,6-trichloropyridine.
These compounds have the same murcko framework: 2,4,6-trichloropyridineSubstitution Reactions: The chlorine atoms in the molecule can undergo substitution reactions with various nucleophiles or electrophiles, depending on the reaction conditions. For example, nucleophilic substitution reactions can replace one or more chlorine atoms with other nucleophilic groups, such as hydroxyl (-OH) or amino (-NH2) groups.
Aromatic Substitution: Being a derivative of pyridine, 2,4,6-trichloropyridine can undergo electrophilic aromatic substitution reactions. Electrophiles can substitute for one of the hydrogen atoms in the pyridine ring, leading to the formation of various substituted products.
Reduction Reactions: The chlorine atoms in 2,4,6-trichloropyridine can be reduced to hydrogens or other substituents under appropriate reaction conditions. Reduction reactions can be achieved using reducing agents like lithium aluminum hydride (LiAlH4) or catalytic hydrogenation.
Metalation Reactions: The pyridine ring in 2,4,6-trichloropyridine can undergo metalation reactions with strong bases like butyllithium (BuLi) or sodium amide (NaNH2). These reactions can lead to the formation of organometallic complexes, which can further participate in various organic transformations.
Functional Group Interconversion: The functional groups present in 2,4,6-trichloropyridine can be interconverted through various chemical reactions, such as oxidation, reduction, or substitution reactions. This allows for the synthesis of different derivatives of pyridine.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−