Chemistry Heterocyclic Building Blocks Pyridines 2,4-dimethylpyridine
Ambeed provide 5 derivatives of 2,4-dimethylpyridine.
These compounds have the same murcko framework: 2,4-dimethylpyridineSubstitution Reactions: Being a derivative of pyridine, 2,4-dimethylpyridine can undergo electrophilic aromatic substitution reactions. For example, it can react with electrophiles such as acyl chlorides or nitro groups under appropriate conditions.
Oxidation: 2,4-dimethylpyridine can be oxidized to the corresponding pyridinium compound under certain conditions, typically using oxidizing agents like chromic acid or potassium permanganate.
Nucleophilic Addition: Depending on the substituents and reaction conditions, 2,4-dimethylpyridine can undergo nucleophilic addition reactions. For instance, it can react with electrophiles at the C-2 or C-4 position to form substituted products.
Reduction: Under specific conditions, 2,4-dimethylpyridine can undergo reduction reactions, typically involving the conversion of the pyridine ring to piperidine or tetrahydropyridine derivatives.
Metalation: Like pyridine, 2,4-dimethylpyridine can undergo metalation reactions with strong bases such as butyllithium or sodium amide, resulting in the formation of metal complexes.
Alkylation or Acylation: 2,4-dimethylpyridine can undergo alkylation or acylation reactions at the nitrogen atom or at the ortho or para positions of the aromatic ring.
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