Chemistry Heterocyclic Building Blocks Pyridines 2,5-difluoropyridine
Ambeed provide 8 derivatives of 2,5-difluoropyridine.
These compounds have the same murcko framework: 2,5-difluoropyridineElectrophilic aromatic substitution: The electron-rich nature of the aromatic ring makes 2,5-difluoropyridine susceptible to electrophilic aromatic substitution reactions, where electrophiles replace one of the hydrogen atoms on the ring.
Nucleophilic aromatic substitution: Depending on the reaction conditions and substituents present on the pyridine ring, nucleophilic aromatic substitution reactions can occur, where a nucleophile replaces a leaving group on the aromatic ring.
Metal-catalyzed reactions: Transition metals can catalyze various reactions involving 2,5-difluoropyridine, such as cross-coupling reactions, C-H activation reactions, and other transformations.
Functional group transformations: The difluoropyridine moiety can participate in various functional group transformations, such as oxidation, reduction, halogenation, and others.
Heterocyclic chemistry: 2,5-difluoropyridine can serve as a building block in the synthesis of various heterocyclic compounds, including fused-ring systems and biologically active molecules.
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(2,5-Difluoropyridin-4-yl)boronic acid