Chemistry Heterocyclic Building Blocks Pyridines 2-(6-benzhydrylpyridin-2-yl)-4,5-dihydrooxazole
Ambeed provide 10 derivatives of 2-(6-benzhydrylpyridin-2-yl)-4,5-dihydrooxazole.
These compounds have the same murcko framework: 2-(6-benzhydrylpyridin-2-yl)-4,5-dihydrooxazole.
Acylation and Alkylation: The oxazole ring can undergo acylation or alkylation reactions, where acyl chlorides or alkyl halides react with the nitrogen atom of the oxazole ring.
Reduction: Reduction of the oxazole ring could lead to the formation of a dihydrooxazole or tetrahydrooxazole, depending on the reaction conditions and reagents used.
Oxidation: Oxidation of the compound may lead to the formation of various oxidation products, depending on the oxidizing agent used.
Ring-Opening Reactions: Depending on the conditions and reagents, the oxazole ring could undergo ring-opening reactions to form open-chain compounds.
Substitution Reactions: Substitution reactions can occur at various positions in the molecule, depending on the electrophilic or nucleophilic nature of the reagents and the availability of reaction sites.
Cyclization Reactions: Depending on the functional groups present in the molecule, intramolecular cyclization reactions can occur to form different cyclic compounds.
Heterocycle Formation: Reactions involving the nitrogen atom of the oxazole ring may lead to the formation of new heterocyclic compounds.
Reductive Amination: The nitrogen atom in the oxazole ring can participate in reductive amination reactions, leading to the introduction of different substituents on the nitrogen atom.
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(S)-2-(6-Benzhydrylpyridin-2-yl)-4-((S)-sec-butyl)-4,5-dihydrooxazole
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(S)-2-(6-Benzhydrylpyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
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(S)-2-(6-Benzhydrylpyridin-2-yl)-4-ethyl-4,5-dihydrooxazole
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(R)-2-(6-Benzhydrylpyridin-2-yl)-4-(tert-butyl)-4,5-dihydrooxazole
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(R)-2-(6-Benzhydrylpyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
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(R)-2-(6-Benzhydrylpyridin-2-yl)-4-ethyl-4,5-dihydrooxazole
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(R)-2-(6-Benzhydrylpyridin-2-yl)-4-methyl-4,5-dihydrooxazole
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(S)-2-(6-Benzhydrylpyridin-2-yl)-4-(tert-butyl)-4,5-dihydrooxazole
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(S)-2-(6-Benzhydrylpyridin-2-yl)-4-methyl-4,5-dihydrooxazole
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(S)-2-(6-Benzhydrylpyridin-2-yl)-4-isobutyl-4,5-dihydrooxazole