Chemistry Organic Building Blocks Amides 2-aminobenzamide
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —C(O)NH2,—NH2).
Friedel-Crafts Acylation: Benzamide can be acylated using Friedel-Crafts acylation reactions. This involves the substitution of a hydrogen atom on the benzene ring with an acyl group from an 【acyl chloride|https://www.ambeed.com/acyl-chlorides.html】 or an 【acid anhydride|https://www.ambeed.com/Anhydrides.html】 in the presence of a Lewis acid catalyst.
Reimer-Tiemann Reaction: Aniline can react with chloroform (CHCl3) and a base to undergo the Reimer-Tiemann reaction, leading to the formation of a salicylaldehyde derivative.
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2-Amino-4-bromo-3-fluoro-5-iodobenzamide