Chemistry Heterocyclic Building Blocks Furans 2,3-dihydrofuran-3-one
Esterification: It can undergo esterification reactions with alcohols or acid chlorides in the presence of a suitable catalyst to form various gamma-butyrolactone derivatives.
Reduction: Reduction of 2,3-dihydrofuran-3-one with reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4) can produce 4-hydroxybutyric acid.
Acylation: It can undergo acylation reactions with acyl halides or anhydrides to form substituted gamma-butyrolactones.
Ring-opening reactions: Depending on the reaction conditions and reagents used, 2,3-dihydrofuran-3-one can undergo ring-opening reactions to form various products. For example, it can be converted to 4-hydroxybutanoic acid through a ring-opening process.
Cyclization: 2,3-Dihydrofuran-3-one can participate in intramolecular cyclization reactions, leading to the formation of cyclic compounds.
Oxidation: It can be oxidized to form gamma-butyrolactone derivatives or other oxidation products under suitable conditions.
Wittig Reaction: It can react with a phosphonium ylide in a Wittig reaction to form substituted 2,3-dihydrofuran-3-one derivatives.
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