Chemistry
Organic Building Blocks
Bromides
2-bromo-1,3-dimethoxybenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—OCH3).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Borohydride Demethylation: Methoxybenzene can undergo demethylation reactions using sodium borohydride (NaBH4) in the presence of a proton source, resulting in the formation of phenol.
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