Chemistry Organic Building Blocks Bromides 2-bromo-1-methoxy-4-methylbenzene
Ambeed provide 4 derivatives of 2-bromo-1-methoxy-4-methylbenzene.
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—OCH3,—CH3).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal alkynes using a palladium catalyst, leading to the formation of substituted alkynes.
Borohydride Demethylation: Methoxybenzene can undergo demethylation reactions using sodium borohydride (NaBH4) in the presence of a proton source, resulting in the formation of phenol.
Sulfonation: Toluene can be sulfonated, leading to the introduction of a sulfonic acid group (-SO3H) onto the benzene ring. This is often carried out using concentrated sulfuric acid.
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2-Bromo-1-methoxy-4-methyl-3-nitrobenzene
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N-(4-Bromo-5-methoxy-2-methylphenyl)acetamide
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1-Bromo-4-fluoro-2-methoxy-5-methylbenzene
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(3-Bromo-2-methoxy-5-methylphenyl)boronic acid