Chemistry
Heterocyclic Building Blocks
Pyridines
2-bromopyridin-3-ol
Substitution Reactions: The bromine atom can undergo substitution reactions with various nucleophiles, such as amines or thiols, leading to the formation of new compounds.
Nucleophilic Addition: The hydroxyl group can undergo nucleophilic addition reactions with electrophiles, such as carbonyl compounds, leading to the formation of hemiacetals or acetals.
Oxidation Reactions: The alcohol group can be oxidized to form the corresponding aldehyde or carboxylic acid under suitable conditions.
Esterification: The alcohol group can undergo esterification reactions with carboxylic acids or acid chlorides to form esters.
Dehydrobromination: The compound can undergo dehydrobromination reactions under appropriate conditions, leading to the formation of an unsaturated compound.
Metalation Reactions: The compound can react with certain metal reagents, such as organolithium or Grignard reagents, leading to the formation of organometallic compounds.
Reduction Reactions: The compound can undergo reduction reactions to convert the bromine atom or the hydroxyl group to different functional groups, depending on the reagent and reaction conditions.
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