Chemistry Heterocyclic Building Blocks Pyridines 2-chloro-3,6-dimethylpyridine
Ambeed provide 4 derivatives of 2-chloro-3,6-dimethylpyridine.
These compounds have the same murcko framework: 2-chloro-3,6-dimethylpyridineNucleophilic Substitution: The chlorine atom in the molecule can be replaced by a nucleophile, such as hydroxide ion, amine, or thiol, resulting in the formation of different substitution products.
Acylation: The compound can undergo acylation reactions, where an acyl group is introduced onto the nitrogen atom or other available nucleophilic sites.
Reduction: Reduction reactions can occur, leading to the conversion of the pyridine ring to a piperidine ring or the reduction of the chloro substituent to a methyl group.
Oxidation: Oxidation reactions may take place, resulting in the formation of various oxidation products depending on the reaction conditions and oxidizing agents used.
Alkylation: The pyridine ring can undergo alkylation reactions, where alkyl groups are introduced onto the nitrogen atom or other available nucleophilic sites.
Halogenation: Further halogenation reactions could occur, particularly if conditions favor such reactions, leading to the introduction of additional halogen atoms onto the pyridine ring.
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