Chemistry Heterocyclic Building Blocks Pyrimidines 2-ethylpyrimidine
Ambeed provide 6 derivatives of 2-ethylpyrimidine.
These compounds have the same murcko framework: 2-ethylpyrimidineNucleophilic Substitution: The nitrogen atoms in the pyrimidine ring can act as nucleophiles in substitution reactions. For example, they can react with alkyl halides or other electrophiles.
Aromatic Substitution: The pyrimidine ring is aromatic, and it can undergo electrophilic aromatic substitution reactions under appropriate conditions.
Oxidation Reactions: The ethyl group can potentially undergo oxidation reactions, depending on the reaction conditions, leading to the formation of corresponding oxidized products.
Alkylation Reactions: The nitrogen atoms in the pyrimidine ring can act as nucleophiles in alkylation reactions, reacting with alkyl halides or other alkylating agents.
Acylation Reactions: The nitrogen atoms can also participate in acylation reactions, where they react with acyl halides or anhydrides to form amide derivatives.
Condensation Reactions: It may participate in condensation reactions with other compounds containing reactive functional groups, forming larger structures.
Reduction Reactions: The pyrimidine ring or the ethyl group may undergo reduction under specific conditions, leading to the formation of reduced products.
Ring-Opening Reactions: Depending on the reaction conditions and substituents, ring-opening reactions may occur, leading to the formation of open-chain structures.
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(4-Amino-2-ethylpyrimidin-5-yl)methanol
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4,6-Dichloro-2-ethylpyrimidin-5-amine
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5-Bromo-2-ethylpyrimidine-4-carboxylic acid