Chemistry Heterocyclic Building Blocks Pyridines 2-fluoro-3-methylpyridine
Ambeed provide 14 derivatives of 2-fluoro-3-methylpyridine.
These compounds have the same murcko framework: 2-fluoro-3-methylpyridineSubstitution Reactions: The fluorine atom and the methyl group can undergo substitution reactions with various electrophiles or nucleophiles, leading to the formation of different derivatives of 2-fluoro-3-methylpyridine.
Metalation: The pyridine ring can be metalated at the 2-position, 3-position, or both, depending on the reaction conditions. This metalation can be useful for further functionalization reactions.
Oxidation: The methyl group can be oxidized to a carboxylic acid, an aldehyde, or a ketone under appropriate conditions.
Reduction: The fluorine atom can be reduced under certain conditions to a fluorine-containing functional group, or the methyl group can be reduced to a methylamine or an alkane.
Condensation Reactions: The pyridine nitrogen can undergo condensation reactions with carbonyl compounds or other electrophiles to form pyridine-containing heterocycles.
Halogenation Reactions: The pyridine ring or the methyl group can undergo halogenation reactions, such as bromination or chlorination, under appropriate conditions.
Acylation and Alkylation Reactions: The pyridine nitrogen or the methyl group can undergo acylation or alkylation reactions with acyl or alkyl halides, respectively.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
Deals click to sign in and save
(6-Fluoro-5-methylpyridin-3-yl)boronic acid
click to sign in and save
2-Fluoro-3-methylpyridine-4-boronic acid