Chemistry Heterocyclic Building Blocks Pyridines 2-isopropoxypyridine
Ambeed provide 16 derivatives of 2-isopropoxypyridine.
These compounds have the same murcko framework: 2-isopropoxypyridineSubstitution Reactions: The isopropoxy group can undergo substitution reactions with various electrophiles or nucleophiles, leading to the formation of new substituted derivatives of 2-isopropoxypyridine.
Acid-Base Reactions: The pyridine ring is basic due to the lone pair of electrons on the nitrogen atom. It can undergo acid-base reactions with acids or bases, resulting in the formation of salts or protonated/deprotonated forms of the compound.
Oxidation Reactions: The pyridine ring can undergo oxidation under appropriate conditions, leading to the formation of various oxidation products.
Nucleophilic Addition Reactions: The pyridine ring can undergo nucleophilic addition reactions with electrophiles, especially at the C-2 position of the pyridine ring.
Metalation Reactions: The pyridine ring can coordinate with transition metal ions to form metal complexes, which may exhibit different reactivity compared to the free ligand.
Esterification Reactions: The hydroxyl group of the isopropoxy moiety can undergo esterification reactions with carboxylic acids or acid chlorides, leading to the formation of ester derivatives.
Reduction Reactions: Depending on the conditions, 2-isopropoxypyridine may undergo reduction reactions, leading to the formation of reduced products.
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(2-Isopropoxypyridin-3-yl)boronic acid
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3-Bromo-2-isopropoxy-5-methylpyridine
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4-(Chloromethyl)-2-isopropoxypyridine hydrochloride
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(6-Isopropoxy-5-methylpyridin-3-yl)boronic acid
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3-Bromo-2-isopropoxy-5-(trifluoromethyl)pyridine