Chemistry Heterocyclic Building Blocks Pyridines 2-methoxy-6-methylpyridine
Ambeed provide 14 derivatives of 2-methoxy-6-methylpyridine.
These compounds have the same murcko framework: 2-methoxy-6-methylpyridineSubstitution Reactions: The methoxy group and the methyl group can undergo substitution reactions. For instance, the methoxy group can be replaced by another functional group under suitable reaction conditions.
Nucleophilic Substitution: The electron-rich nature of the methoxy group can make it susceptible to nucleophilic attack, leading to substitution reactions.
Acylation: The pyridine nitrogen atom can undergo acylation reactions, where an acyl group (-C(=O)R) replaces a hydrogen atom on the nitrogen.
Alkylation: The pyridine nitrogen can also undergo alkylation reactions, where an alkyl group replaces a hydrogen atom on the nitrogen.
Oxidation Reactions: The methyl group can be oxidized to a carboxylic acid group under suitable conditions.
Reduction Reactions: The pyridine ring can be reduced under certain conditions, leading to the formation of piperidine derivatives.
Grignard Reaction: The compound can react with Grignard reagents to form various substituted derivatives.
Heterocyclic Chemistry: Being a pyridine derivative, it can participate in various heterocyclic chemistry reactions, such as ring-closure reactions to form fused ring systems or other heterocyclic compounds.
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6-Methoxy-2-methylpyridin-3-amine dihydrochloride
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(6-Methoxy-2-methylpyridin-3-yl)boronic acid
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(2-Methoxy-6-methylpyridin-3-yl)boronic acid
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(6-Methoxy-2-methylpyridin-3-yl)methanamine dihydrochloride
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(2-Methoxy-6-methylpyridin-4-yl)boronic acid
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4-(Chloromethyl)-2-methoxy-6-methylpyridine