Chemistry Heterocyclic Building Blocks Triazoles 2-phenyl-2H-1,2,3-triazole

2-phenyl-2H-1,2,3-triazole

Substitution Reactions: The phenyl group in the molecule can undergo electrophilic aromatic substitution reactions, such as nitration, halogenation, and Friedel-Crafts acylation or alkylation. Reductive Reactions: The triazole ring can undergo reductive reactions. For example, it can be reduced to the corresponding amine using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4). Functional Group Transformations: Various functional groups can be introduced or modified in the molecule using standard organic chemistry reactions. For instance, you can perform acylation, alkylation, or oxidation reactions on the triazole ring or the phenyl group. Metal-Catalyzed Reactions: Transition metal-catalyzed reactions, such as cross-coupling reactions, can be applied to 2-phenyl-2H-1,2,3-triazole to form new carbon-carbon or carbon-heteroatom bonds. Nucleophilic Substitution: If there are suitable leaving groups on the molecule, nucleophilic substitution reactions can occur at those positions. Condensation Reactions: 2-Phenyl-2H-1,2,3-triazole can undergo condensation reactions with compounds containing active hydrogen atoms, leading to the formation of new heterocyclic compounds. Ring Opening: Depending on the conditions and substituents, ring-opening reactions of the triazole ring can occur, leading to various products.

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(5aS,10bR)-2-phenyl-2,5a,6,10b-tetrahydro-4H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-11-ium 1-(phenylsulfonyl)-1H-1,2,4-triazole 1-benzyl-1H-1,2,3-triazole 1-benzyl-1H-1,2,4-triazole 1-methyl-1H-1,2,3-triazole 1-methyl-1H-1,2,4-triazole 1-methyl-1H-benzo[d][1,2,3]triazole 1-phenethyl-1H-1,2,4-triazole 1-phenyl-1H-1,2,3-triazole 1-phenyl-1H-1,2,4-triazole 1H-1,2,4-triazol-3-amine 1H-1,2,4-triazol-5-amine 1H-benzo[d][1,2,3]triazol-1-ol 2-bromo-[1,2,4]triazolo[1,5-a]pyridine 2-phenyl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazol-4-ium 2-phenyl-2H-1,2,3-triazole 2-phenyl-2H-benzo[d][1,2,3]triazole 2H-1,2,3-triazole 4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole 4-phenyl-4H-1,2,4-triazole 4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine 4H-1,2,4-triazole 5-bromo-1H-1,2,4-triazole 5-bromo-1H-benzo[d][1,2,3]triazole 5-fluoro-1H-benzo[d][1,2,3]triazole 6-bromo-[1,2,4]triazolo[1,5-a]pyridine 6-bromo-[1,2,4]triazolo[4,3-a]pyridine 8-bromo-[1,2,4]triazolo[1,5-a]pyridine [1,2,4]triazolo[1,5-a]pyrazine [1,2,4]triazolo[1,5-a]pyridin-2-amine [1,2,4]triazolo[4,3-a]pyridin-3-ylmethanamine ethyl 1H-1,2,4-triazole-3-carboxylate

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amino-triazole amino-triazolopyrimidine benzotriazole benzotriazole-ethylamine bromo-triazole bromotriazolopyridine chloro-triazolopyridazine chloro-triazolopyridine chloro-triazolopyrimidine fluoro-triazolopyridine indenotriazolooxazine methyl-triazole methyl-triazolopyridine methyl-triazolopyrimidine nitro-triazole phenyl-triazole piperidine-triazole pyrrolotriazole triazol-amine triazol-benzene triazol-one triazol-oxazine triazol-pyridine triazole-carbonitrile triazole-carboxylate triazole-carboxylic triazole-carboxylic-acid triazole-methanol triazolopyrazine triazolopyridazine triazolopyridin-amine triazolopyridine triazolopyridine-carboxylate triazolopyridine-carboxylic triazolopyrimidine

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