Chemistry Heterocyclic Building Blocks Pyridines 3-(benzyloxy)pyridine
Ambeed provide 19 derivatives of 3-(benzyloxy)pyridine.
These compounds have the same murcko framework: 3-(benzyloxy)pyridine.
Nucleophilic Substitution: The benzyl ether group can be cleaved by nucleophiles, such as strong acids or bases, or by reaction with electrophiles like alkyl halides. This can result in the formation of a substituted pyridine derivative.
Nucleophilic Aromatic Substitution: The pyridine ring can undergo nucleophilic aromatic substitution reactions, particularly if there are suitable electron-withdrawing or electron-donating groups on the ring.
Friedel-Crafts Acylation or Alkylation: The benzyl ether group can be modified through Friedel-Crafts acylation or alkylation reactions, leading to the introduction of acyl or alkyl groups onto the benzene ring.
Oxidation: The pyridine ring can undergo various oxidation reactions, leading to the formation of pyridinium salts or other oxidized derivatives.
Reduction: Reduction of the compound can be achieved using reducing agents, leading to the removal of functional groups or the conversion of the pyridine ring to piperidine.
Grignard Reaction: The compound can react with Grignard reagents to form various products, depending on the nature of the Grignard reagent and reaction conditions.
Dehydrogenation: Under certain conditions, the compound can undergo dehydrogenation reactions, leading to the formation of a double bond in the pyridine or benzene ring.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine
Deals click to sign in and save
(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Deals click to sign in and save
3-(Benzyloxy)-5-bromo-2-chloropyridine
click to sign in and save
Methyl 3-(benzyloxy)-4,6-dibromopicolinate
click to sign in and save
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
click to sign in and save
3-(Benzyloxy)-6-bromo-4-methoxypicolinic acid
Deals click to sign in and save
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
click to sign in and save
3-(Benzyloxy)-2-(chloromethyl)pyridine
click to sign in and save
(R)-Methyl 2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate