Chemistry Heterocyclic Building Blocks Pyridines 3-(chloromethyl)pyridine
Ambeed provide 22 derivatives of 3-(chloromethyl)pyridine.
These compounds have the same murcko framework: 3-(chloromethyl)pyridineNucleophilic Substitution: The chlorine atom can be replaced by a nucleophile (e.g., hydroxide ion, amine) to form various substituted products.
Grignard Reaction: 3-(chloromethyl)pyridine can react with a Grignard reagent to form a new carbon-carbon bond, resulting in substituted products.
Reduction: The chloromethyl group can be reduced to a methyl group using reducing agents such as lithium aluminum hydride (LiAlH4) or hydrogen gas with a metal catalyst.
Alkylation: It can undergo alkylation reactions with alkyl halides in the presence of a base to yield products with substituted alkyl groups.
Acylation: Reacting with acyl chlorides or acid anhydrides can lead to the formation of ketones or amides.
Ring Closure Reactions: The chloromethyl group can participate in ring closure reactions, leading to the formation of cyclic compounds.
Oxidation: Under specific conditions, the compound can undergo oxidation reactions, potentially leading to the formation of products with higher oxidation states.
Elimination Reactions: It can undergo elimination reactions, resulting in the formation of alkenes or other elimination products.
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3-Bromo-5-(chloromethyl)pyridine hydrochloride
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5-(Chloromethyl)-2-(difluoromethoxy)pyridine
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5-(Chloromethyl)picolinonitrile hydrochloride
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3-(Chloromethyl)-5-methylpyridine hydrochloride
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3-(Chloromethyl)-4-methylpyridine hydrochloride
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5-(Chloromethyl)-2-(trifluoromethyl)pyridine
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3,5-Bis(chloromethyl)pyridine hydrochloride
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3-(Chloromethyl)-5-methoxypyridine hydrochloride
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3-Chloro-5-(chloromethyl)pyridine hydrochloride
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Methyl 5-(chloromethyl)nicotinate hydrochloride
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3-(Chloromethyl)-2-methoxypyridine hydrochloride
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3-(Chloromethyl)-5-fluoropyridine hydrochloride
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3-(Chloromethyl)-2-methylpyridine hydrochloride
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5-(Chloromethyl)-2-methylpyridine hydrochloride
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5-(Chloromethyl)nicotinonitrile hydrochloride
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2-Bromo-5-(chloromethyl)pyridine hydrochloride